The error looks like:
"Critical: (110.6) CNcbiRegistry: Syntax error in system-wide configuration file: NCBI C++ Exception: "..........\src\corelib\ncbireg.cpp", line 660: Error: ncbi::IRWRegistry ::x_Read() - Badly placed '\' in the registry value: 'ROOT=J:\nASNLOAD=J:\BioEdi t\tables\nDATA=J:\BioEdit\tables\' (m_Pos = 4)
Error: NCBI C++ Exception: "..........\src\corelib\ncbireg.cpp", line 660: Error: ncbi::IRWRegistry ::x_Read() - Badly placed '\' in the registry value: 'ROOT=J:\nASNLOAD=J:\BioEdi t\tables\nDATA=J:\BioEdit\tables\' (m_Pos = 4)"
This error is reported from the NCBI binaries and not from OmicsBox.
According to the following thread at Biostars the problem is related to the Bioedit software.
Do you have this software installed on your computer?
We recommend moving the configuration setting file named “ncbi.ini” in the Windows folder to a different place.
Once moved, try to run the LocalBlast again.